* ''Lara Croft: Tomb Raider'' (2001): "[[Deep]]".
* ''Resident Evil'' (2002): While Alice battles the mutated dogs, "[[Fist Fuck]]" soundtracks the assault.
* ''Saw'' (2003 short film): Intro and end credits have clips from the ''[[Fixed]]'' remix of "[[Happiness In Slavery (song)|Happiness In Slavery]]".
* ''School of Rock'' (2003): A NIN sticker can be seen among the band stickers in Dewey's bedroom.
* ''The Machinist'' (2004): Writer Scott Kosar is a fan of Nine Inch Nails, and named Christian Bale's character Trevor Reznik in tribute to Reznor. His original script had NIN lyrics on the first page, the promotional poster for the film has a backwards 'N' (as in the NIИ logo), and early press articles described Reznik as going through "[[The Downward Spiral (halo)|a downward spiral]]."